Plant-Derived Nanoscale-Encapsulated Antioxidants for Oral and Topical Uses: A Brief Review

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10
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10

초록

Several plant-based nanoscale-encapsulated antioxidant compounds (rutin, myricetin, beta-carotene, fisetin, lycopene, quercetin, genkwanin, lutein, resveratrol, eucalyptol, kaempferol, glabridin, pinene, and whole-plant bio-active compounds) are briefly introduced in this paper, along with their characteristics. Antioxidants' bioavailability has become one of the main research topics in bio-nanomedicine. Two low patient compliance drug delivery pathways (namely, the oral and topical delivery routes), are described in detail in this paper, for nanoscale colloidal systems and gel formulations. Both routes and/or formulations seek to improve bioavailability and maximize the drug agents' efficiency. Some well-known compounds have been robustly studied, but many remain elusive. The objective of this review is to discuss recent studies and advantages of nanoscale formulations of plant-derived antioxidant compounds.

키워드

nanomedicine; bio-active compounds; formulation; SOLID LIPID NANOPARTICLES; DRUG-DELIVERY SYSTEMS; CELL-CYCLE ARREST; IN-VITRO; FORMULATION OPTIMIZATION; BETA-CAROTENE; PHYSALIS-ALKEKENGI; OXIDATIVE STRESS; ALPHA-PINENE; ANTIMICROBIAL ACTIVITY
제목
Plant-Derived Nanoscale-Encapsulated Antioxidants for Oral and Topical Uses: A Brief Review
저자
Kim, Seong-Hyeon; Lee, Young-Chul
DOI
10.3390/ijms23073638
발행일
2022-04
유형
Review
저널명
International Journal of Molecular Sciences
권
23
호
7