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The therapeutic effects on U87 and SAS cells using Proton Linac based Boron Neutron Capture Therapy in Korea
- Seo, Il Hyeok;
- Seo, Hyo Jung;
- Na, Dasom;
- Yoo, Mooyoung;
- Schwint, Amanda;
- ... Park, Kawngwoo;
- ... Yee, Gi-Taek;
- ... Kim, Woo-Kyung;
- 외 5명
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2초록
A proton linac based boron neutron capture therapy system (A-BNCT, 10MeV, 4mA) was successfully developed in Korea. We performed in vitro experiments with U87 and SAS cells and revealed the efficacy of a binary therapy BNCT using epithermal neutrons and boronophenylalanine (BPA). The results revealed that BNCT showed cancer cell selectivity and caused cell death. Further in vitro studies can be a valuable method to characterize an A-BNCT system. We expect BNCT to become a treatment option for cancer patients.
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TUMOR; LAT1; HEAD
- 제목
- The therapeutic effects on U87 and SAS cells using Proton Linac based Boron Neutron Capture Therapy in Korea
- 저자
- Seo, Il Hyeok; Seo, Hyo Jung; Na, Dasom; Yoo, Mooyoung; Schwint, Amanda; Kim, Se Hyun; Lee, Jeongwoo; Jeon, Sang-June; Choi, Jae Won; Kim, Woo Hyoung; Park, Kawngwoo; Yee, Gi-Taek; Kim, Woo-Kyung
- 발행일
- 2023-07
- 유형
- Article
- 권
- 197