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Screening of herbal medicines from korea with inhibitory activity on advanced glycation end products formation (XII)
- Choi, S.J.;
- Kim, Y.S.;
- Kim, J.H.;
- Kim, J.S.
SCOPUS
1초록
Advanced glycation end products (AGEs) have been implicated in diabetic complications. In this study, the inhibitory effect on AGEs formation of 156 Korean herbal medicines has been evaluated. Among them, 15 Korean herbal medicines were showed to have significant effect (IC50: <10 μg/ml) compared to positive reference, aminoguandine (IC50: 76.47±4.81 μg/ ml). Especially, four herbal medicines, Alnus firma (leaves, IC50: 3.25±0.10 μg/ml), Juncus decipiens (whole plants, IC50: 4.30±0.44 μg/ml), Smilax china (stems, IC50: 3.55±0.21 μg/ml), and Vicia amoena (Aerial parts, IC50: 4.25±0.06 μg/ml) showed more potent inhibitory activity approximately 8-24 fold) than the positive control aminoguanidine. © 2015, Korean Society of Pharmacognosy. All rights reserved.
키워드
- 제목
- Screening of herbal medicines from korea with inhibitory activity on advanced glycation end products formation (XII)
- 제목 (타언어)
- 한국 약용식물의 최종당화산물 생성저해활성 검색 (XII)
- 저자
- Choi, S.J.; Kim, Y.S.; Kim, J.H.; Kim, J.S.
- 발행일
- 2015-09
- 유형
- Article
- 저널명
- 생약학회지
- 권
- 46
- 호
- 3
- 페이지
- 250 ~ 259
- 언어
- KOR
- 출판사
- Korean Society of Pharmacognosy
- 발행국가
- 대한민국
- 분량
- 10 페이지
- ISSN
- P 0253-3073