Recent advances in the management of multiple myeloma: clinical impact based on resource-stratification. Consensus statement of the Asian Myeloma Network at the 16th international myeloma workshop

  • Tan, Daryl; 
  • Lee, Jae Hoon; 
  • Chen, Wenming; 
  • Shimizu, Kazuyuki; 
  • Hou, Jian; 
  • 외 9명
Citations

WEB OF SCIENCE

14
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SCOPUS

19

초록

Predicated on our improved understanding of the disease biology, we have seen remarkable advances in the management of multiple myeloma over the past few years. Recently approved drugs have radically transformed the treatment paradigm and improved survivals of myeloma patients. The progress has necessitated revision of the diagnostic criteria, risk-stratification and response definition. The huge disparities in economy, healthcare infrastructure and access to novel drugs among different Asian countries will hinder the delivery of optimum myeloma care to patients managed in resource-constrained environments. In the light of the tremendous recent changes and evolution in myeloma management, it is timely that the resource-stratified guidelines from the Asian Myeloma Network be revised to provide updated recommendations for Asia physicians practicing under various healthcare reimbursement systems. This review will highlight the most recent advances and our recommendations on how they could be integrated in both resource-abundant and resource-constrained facilities.

키워드

Myeloma; resource-stratified; novel agents; STEM-CELL TRANSPLANTATION; MINIMAL RESIDUAL DISEASE; LENALIDOMIDE PLUS DEXAMETHASONE; NEWLY-DIAGNOSED MYELOMA; LOW-DOSE DEXAMETHASONE; INELIGIBLE PATIENTS; STAGING SYSTEM; HIGH-RISK; PROGNOSTIC-SIGNIFICANCE; LACTATE-DEHYDROGENASE
제목
Recent advances in the management of multiple myeloma: clinical impact based on resource-stratification. Consensus statement of the Asian Myeloma Network at the 16th international myeloma workshop
저자
Tan, Daryl; Lee, Jae Hoon; Chen, Wenming; Shimizu, Kazuyuki; Hou, Jian; Suzuki, Kenshi; Nawarawong, Weerasak; Huang, Shang-Yi; Chim, Chor Sang; Kim, Kihyun; Kumar, Lalit; Malhotra, Pankaj; Chng, Wee Joo; Durie, Brian
DOI
10.1080/10428194.2018.1427858
발행일
2018-10
유형
Article
저널명
Leukemia and Lymphoma
권
59
호
10
페이지
2305 ~ 2317