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한국약용식물의 최종당화산물 생성저해활성 검색(VII)
Screening of Korean Herbal Medicines with Inhibitory Activity on Advanced Glycation End Products Formation (VII)
- 최소진;
- 김영숙;
- 송유진;
- 이윤미;
- 김주환;
- 외 1명
초록
In this study, 49 Korean herbal medicines have been investigated with an in vitro evaluation system using glycation end products (AGEs) formation inhibitory activity. Of these, 18 herbal medicines (IC_50<50 µg/ml) were found to have significant AGEs formation inhibitory activity. Of these, five herbal medicines (IC_50<10 µg/ml) were found to have significant AGEs formation inhibitory activity. Particularly, Mallotus japonicus (twigs and leaves), Rhus javanica (twigs and leaves), Boehmeria nivea (whole plants), Quercus acuta (stems), and Eurya japonica (stems) showed more potent inhibitory activity (approximately 9-37 fold) than the positive control aminoguanidine (IC_50=76.47 µg/ml).
키워드
Advanced glycation end products (AGEs); Diabetic complications; Korean herbal medicines
- 제목
- 한국약용식물의 최종당화산물 생성저해활성 검색(VII)
- 제목 (타언어)
- Screening of Korean Herbal Medicines with Inhibitory Activity on Advanced Glycation End Products Formation (VII)
- 저자
- 최소진; 김영숙; 송유진; 이윤미; 김주환; 김진숙
- 발행일
- 2012-12
- 저널명
- 생약학회지
- 권
- 43
- 호
- 4
- 페이지
- 345 ~ 351
- 언어
- KOR
- 출판사
- 한국생약학회
- 발행국가
- 대한민국
- 분량
- 7 페이지
- ISSN
- P 0253-3073