Screening of Korean herbal medicines with inhibitory effect on aldose reductase (IX)

Choi, S.-J.; Kim, Y.S.; Kim, J.H.; Kim, J.S.

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Screening of Korean herbal medicines with inhibitory effect on aldose reductase (IX)

한국 약용식물 추출물의 알도즈 환원 효소 억제 효능 검색(IX)

Choi, S.-J.;
Kim, Y.S.;
Kim, J.H.;
Kim, J.S.

Citations

SCOPUS

2

초록

Aldose reductase (AR) has been demonstrated to play important role in the development of the diabetic complications such as diabetic retinopathy, diabetic neuropathy and diabetic nephropathy. To discover novel treatments for diabetic complications from natural sources, 69 Korean herbal medicines have been investigated for inhibitory activities on AR. Among them, 7 herbal medicines, Eleutherococcus sessiliflorus (stems), Artemisia japonica (whole plants), Wisteria floribunda (leaves), Eurya japonica (stems, twigs and leaves, leaves), Ampelopsis brevipedunculata (stems) exhibited a significant inhibitory activity compared with 3,3-tetramethyleneglutaric acid as positive control. © 2015, Korean Society of Pharmacognosy. All rights reserved.

키워드

Aldose reductase inhibitor; Diabetic complications; Korean herbal medicines; aldehyde reductase; herbaceous agent; tetramethyleneglutaric acid; Ampelopsis brevipedunculata; Artemisia japonica; Article; controlled study; diabetic nephropathy; diabetic neuropathy; diabetic retinopathy; drug screening; Eurya japonica; herbal medicine; Korea; medicinal plant; nonhuman; plant leaf; plant stem; Wisteria floribunda

제목: Screening of Korean herbal medicines with inhibitory effect on aldose reductase (IX)

제목 (타언어): 한국 약용식물 추출물의 알도즈 환원 효소 억제 효능 검색(IX)

저자: Choi, S.-J.; Kim, Y.S.; Kim, J.H.; Kim, J.S.

발행일: 2014-12

유형: Article

저널명: 생약학회지

권: 45

호: 4

페이지: 354 ~ 358

언어: KOR

출판사: Korean Society of Pharmacognosy

발행국가: 대한민국

분량: 5 페이지

ISSN: P 0253-3073