Mycobacterium intracellulare Pulmonary Disease with Endobronchial Caseation in a Patient Treated with Methotrexate

Park, Jin Sun; Jung, Eul Sik; Choi, Woosuk; Park, Soo Yong; Rim, Min Young; Yu, Inku; Park, Hyeonsu; Lee, Sang Min; Park, Jeong-Woong; Jeong, Sung Hwan; Lee, Sang Pyo; Park, Sanghui

doi:10.4046/trd.2013.75.1.28

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Mycobacterium intracellulare Pulmonary Disease with Endobronchial Caseation in a Patient Treated with Methotrexate

Park, Jin Sun;
Jung, Eul Sik;
Choi, Woosuk;
Park, Soo Yong;
Rim, Min Young;
... Lee, Sang Min;
... Park, Jeong-Woong;
... Jeong, Sung Hwan;
... Lee, Sang Pyo;
외 3명

Citations

SCOPUS

5

초록

Methotrexate (MTX) has been established as a standard disease-modifying anti-rheumatic drug. If adequate disease control is achieved for a reasonable period of time, tapering the MTX dosage is recommended because the chronic use of MTX can result in opportunistic infection. We present here a case of a woman with rheumatoid arthritis taking MTX, and the woman developed actively caseating endobronchial Mycobacterium intracellulare disease with pulmonary infiltrations. After discontinuing the MTX, the patient was able to tolerate 18 months of antimycobacterial treatment without flare ups of rheumatoid arthritis, and she completely recovered from nontuberculous mycobacterial respiratory disease. Copyright © 2013 The Korean Academy of Tuberculosis and Respiratory Diseases. All rights reserved.

키워드

Arthiritis, rheumatoid; Bronchial diseases; Methotrexate; Nontuberculous mycobacteria; Tuberculosis, pulmonary; C reactive protein; ethambutol; hydroxychloroquine sulfate; isoniazid; methotrexate; nabumetone; paracetamol; pyrazinamide; rifampicin; adult; anorexia; article; bacterium culture; body temperature; breathing rate; bronchoscopy; bronchus biopsy; case report; disease exacerbation; drug withdrawal; dyspnea; erythrocyte sedimentation rate; female; heart rhythm; human; lung infiltrate; lung tuberculosis; lymphadenopathy; Mycobacterium intracellulare; night sweat; rheumatoid arthritis; thorax pain; thorax radiography; treatment duration; treatment response

제목: Mycobacterium intracellulare Pulmonary Disease with Endobronchial Caseation in a Patient Treated with Methotrexate

저자: Park, Jin Sun; Jung, Eul Sik; Choi, Woosuk; Park, Soo Yong; Rim, Min Young; Yu, Inku; Park, Hyeonsu; Lee, Sang Min; Park, Jeong-Woong; Jeong, Sung Hwan; Lee, Sang Pyo; Park, Sanghui

DOI: 10.4046/trd.2013.75.1.28

발행일: 2013-07

유형: Article

저널명: Tuberculosis and Respiratory Diseases

권: 75

호: 1

페이지: 28 ~ 31

언어: ENG

출판사: 대한결핵및호흡기학회

발행국가: 대한민국

분량: 4 페이지

ISSN: E 2005-6184
P 1738-3536