Three new oleanane-type triterpenoidal glycosides from impatiens balsamina and their biological activity

  • Lee, T.H.; 
  • Suh, W.S.; 
  • Subedi, L.; 
  • Kim, S.Y.; 
  • Choi, S.U.; 
  • 외 2명
Citations

WEB OF SCIENCE

7
Citations

SCOPUS

12

초록

Three new oleanane-type triterpenoidal glycosides, imbalosides A–C (1–3), were isolated from the white flowers of Impatiens balsamina. The structures of these phytochemical constituents (1–3) were elucidated through 1D and 2D Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS) data analyses followed by chemical methods. All the characterized compounds (1–3) were evaluated for their antiproliferative activity against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and BT549) and their anti-neuroinflammatory activity on the basis of inhibition levels of nitric oxide (NO) in the lipopolysaccharide (LPS)-stimulated murine microglia BV-2 cell lines. © 2020 by the authors. Licensee MDPI, Basel, Switzerland.

키워드

Anti-neuroinflammation; Balsaminaceae; Cytotoxicity; Impatiens balsamina; Triterpenoidal glycosides
제목
Three new oleanane-type triterpenoidal glycosides from impatiens balsamina and their biological activity
저자
Lee, T.H.; Suh, W.S.; Subedi, L.; Kim, S.Y.; Choi, S.U.; Lee, K.R.; Kim, C.S.
DOI
10.3390/plants9091083
발행일
2020-09
유형
Article
저널명
Plants
권
9
호
9
페이지
1 ~ 9