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Screening of Chinese Herbal Medicines with Inhibitory Effect on Aldose Reductase (X)
중국 약용식물 추출물의 알도즈 환원 효소 억제 효능 검색(X)
- Choi, S.-J.;
- Kim, Y.S.;
- Kim, J.H.;
- Kim, J.S.
Citations
SCOPUS
2초록
Aldose reductase (AR) is the key enzyme of the polyol pathway in the development of the diabetic complications. Sixty seven Chinese herbal medicines have been investigated for inhibitory activities on AR. Among them, 7 herbal medicines, Buddleja crispa (twigs and leaves), Taiwania flousiana (twigs and leaves), Sloanea hemsleyana (fruits), Euphorbia nemetocypha (whole plants), Photinia glomerata (twigs and leaves), Vitex yunnanensis (twigs and leaves) exhibited a significant inhibitory activity against AR. Particularly, S. hemsleyana and V. yunnanensis showed 1.2-4.5 times more potent inhibitory activity than the positive control, 3,3-tetramethyleneglutaric acid (TMG). © 2015, Korean Society of Pharmacognosy. All rights reserved.
키워드
Aldose reductase inhibitor; Chinese herbal medicines; Diabetic complications; aldehyde reductase; tetramethyleneglutaric acid; Article; Buddleja crispa; Chinese; Chinese medicine; controlled study; drug screening; Euphorbia nemetocypha; fruit; herbal medicine; nonhuman; Photinia glomerata; plant; plant leaf; Sloanea hemsleyana; Taiwania flousiana; Vitex yunnanensis
- 제목
- Screening of Chinese Herbal Medicines with Inhibitory Effect on Aldose Reductase (X)
- 제목 (타언어)
- 중국 약용식물 추출물의 알도즈 환원 효소 억제 효능 검색(X)
- 저자
- Choi, S.-J.; Kim, Y.S.; Kim, J.H.; Kim, J.S.
- 발행일
- 2014-12
- 유형
- Article
- 저널명
- 생약학회지
- 권
- 45
- 호
- 4
- 페이지
- 359 ~ 365
- 언어
- KOR
- 출판사
- Korean Society of Pharmacognosy
- 발행국가
- 대한민국
- 분량
- 7 페이지
- ISSN
- P 0253-3073