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Impact of genetic variants on clinical outcome after percutaneous coronary intervention in elderly patients
- Cha, Jung-Joon;
- Park, Jae Hyoung;
- Joo, Hyung Joon;
- Hong, Soon Jun;
- Ahn, Tae Hoon;
- ... Kang, Woong Chol;
- 외 11명
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3초록
Elderly patients treated with percutaneous coronary intervention (PCI) have a higher risk of both ischemic and bleeding complications than younger patients. However, few studies have reported how genetic information of elderly patients treated with PCI affects clinical outcomes. We investigated the impact of genetic variants on clinical outcomes in elderly patients. Correlations between single-nucleotide polymorphisms (CYP2C19 and P2Y12 receptor gene G52T polymorphism) and clinical outcomes were analyzed in 811 elderly patients (≥75 years of age) from a prospective multicenter registry. The primary endpoint was a composite of myocardial infarction and death. Secondary endpoints were an individual event of death, cardiac death, myocardial © 2021 Cha et al. All rights reserved.
키워드
- 제목
- Impact of genetic variants on clinical outcome after percutaneous coronary intervention in elderly patients
- 저자
- Cha, Jung-Joon; Park, Jae Hyoung; Joo, Hyung Joon; Hong, Soon Jun; Ahn, Tae Hoon; Kim, Byeong-Keuk; Shin, WonYong; Ahn, Sung Gyun; Yoon, JungHan; Kim, Yong Hoon; Cho, Yun-Hyeong; Kang, Woong Chol; Kim, Weon; Lim, Young-Hyo; Gwon, Hyeon Cheol; Choi, Woong Gil; Lim, Do-Sun
- 발행일
- 2021-03-15
- 유형
- Article
- 저널명
- AGING-US
- 권
- 13
- 호
- 5
- 페이지
- 6506 ~ 6524
- 언어
- ENG
- 출판사
- Impact Journals LLC
- 발행국가
- 미국
- 분량
- 19 페이지
- ISSN
- P 1945-4589