Botulinum Toxin Type A for Pediatric Torticollis: A Review of Clinical Research

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초록

Pediatric torticollis, predominantly resulting from congenital muscular torticollis, is characterized by unilateral shortening of the sternocleidomastoid muscle, leading to head tilt and limited cervical mobility. Conventional management primarily involves physical therapy and repositioning strategies, with most infants achieving full recovery. However, a subset of patients exhibits persistent symptoms despite conservative treatment. Botulinum toxin type A (BoNT-A) has emerged as a minimally invasive adjunct intervention that targets muscular hypertonicity by inhibiting acetylcholine release at neuromuscular junctions. This scoping review synthesizes clinical evidence from six studies, including randomized controlled trials and case reports, assessing the efficacy and safety of BoNT-A in pediatric torticollis. Results indicate consistent improvements in range of motion, head posture correction, and patient satisfaction, with rare and mild adverse events such as local bruising and transient muscle weakness. Despite promising outcomes, variability in dosing, injection protocols, and follow-up durations underscores the need for standardized treatment guidelines and further high-quality research. These findings support BoNT-A as a valuable therapeutic option for refractory pediatric torticollis, warranting integration into multidisciplinary care frameworks.

키워드

botulinum toxincongenital muscular torticollisbotulinum toxin type ACONGENITAL MUSCULAR TORTICOLLISINFANTSDETERMINANTSSAFETY
제목
Botulinum Toxin Type A for Pediatric Torticollis: A Review of Clinical Research
저자
Kwon, Na-YoenSung, Soo-HyunSung, Hyun-Kyung
DOI
10.3390/toxins17110543
발행일
2025-11
유형
Review
저널명
Toxins
17
11