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Screening of Korean herbal medicines with inhibitory effect on Aldose reductase (VIII)
한국 약용식물 추출물의 알도즈 환원 효소 억제 효능 검색 (VIII)
- Lee, Y.M.;
- Kim, Y.S.;
- Kim, J.H.;
- Kim, J.S.
Citations
SCOPUS
3초록
Aldose reductase (AR) plays a central role in the development of the diabetic complications. Eighty one Korean herbal medicines have been investigated for inhibitory activities on AR. Among them, fourteen herbal medicines exhibited a significant inhibitory activity compared with 3,3-tetramethyleneglutaric acid (TMG) as positive control. Particularly, Xanthium strumarium (fruit, whole plant), Ilex cornuta (stem and leaf), Vitex rotundifolia(stem), Sophora flavescens (whole plant), Platycarya stobilacea (flower) showed two times more potent inhibitory activity than 3,3-tetramethyleneglutaric acid (TMG).
키워드
Aldose reductase inhibitor; Diabetic complications; Korean herbal medicines; aldehyde reductase; Ilex cornuta extract; plant extract; Platycarya stobilacea extract; Sophora flavescens extract; tetramethyleneglutaric acid; unclassified drug; Vitex rotundifolia extract; xanthium strumarium extract; article; controlled study; diabetes mellitus; enzyme inhibition; herbal medicine; Ilex; latycarya stobilacea; medicinal plant; nonhuman; Platycarya stobilacea; screening; Sophora flavescens; Vitex rotundifolia; Xanthium
- 제목
- Screening of Korean herbal medicines with inhibitory effect on Aldose reductase (VIII)
- 제목 (타언어)
- 한국 약용식물 추출물의 알도즈 환원 효소 억제 효능 검색 (VIII)
- 저자
- Lee, Y.M.; Kim, Y.S.; Kim, J.H.; Kim, J.S.
- 발행일
- 2013-06
- 유형
- Article
- 저널명
- 생약학회지
- 권
- 44
- 호
- 2
- 페이지
- 168 ~ 175
- 언어
- KOR
- 출판사
- 한국생약학회
- 발행국가
- 대한민국
- 분량
- 8 페이지
- ISSN
- P 0253-3073