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Screening of Korean herbal medicines with inhibitory activity on advanced glycation end products formation (IX)
한국약용식물의 최종당화산물 생성저해활성 검색 (IX)
- Lee, Y.M.;
- Kim, Y.S.;
- Kim, J.H.;
- Kim, J.S.
Citations
SCOPUS
4초록
In this study, 64 Korean herbal medicines have been investigated with an in vitro evaluation systems using glycation end products (AGEs) formation inhibitory activity. Of these, 30 herbal medicines (IC50<50 μg/ml) were found to have significant AGEs formation inhibitory activity. Of these, four herbal medicines (IC50<5 μg/ml) were found to have significant AGEs formation inhibitory activity. Particularly, Cornus controversa (branches and leaves), Acer ginnala (stems and leaves), Platycarya strobilacea (flowers) and Picrasma quassioides (stems), showed more potent inhibitory activity (approximately 17- 27 fold) than the positive control aminoguanidine (IC50=77.04 μg/ml).
키워드
Advanced glycation end products (AGEs); Diabetic complications; Korean herbal medicines; advanced glycation end product; aminoguanidine; Acer ginnala; article; controlled study; Cornus controversa; drug inhibition; drug screening; IC 50; Korean medicine; medicinal plant; nonhuman; Picrasma quassioides; Platycarya strobilacea
- 제목
- Screening of Korean herbal medicines with inhibitory activity on advanced glycation end products formation (IX)
- 제목 (타언어)
- 한국약용식물의 최종당화산물 생성저해활성 검색 (IX)
- 저자
- Lee, Y.M.; Kim, Y.S.; Kim, J.H.; Kim, J.S.
- 발행일
- 2013-09
- 유형
- Article
- 저널명
- 생약학회지
- 권
- 44
- 호
- 3
- 페이지
- 298 ~ 304
- 언어
- KOR
- 출판사
- 한국생약학회
- 발행국가
- 대한민국
- 분량
- 7 페이지
- ISSN
- P 0253-3073