심원식 프로필 사진

심원식

Shim, Won-Sik

약학대학

약학과

Web Of Science ORCID

연구분야

  • Calcium imaging, 
  • Ion channel, 
  • Pruritus, 
  • 가려움증, 
  • 이온채널, 
  • 칼슘이미징

자료 필터

자료유형

발행연도

2013 ~ 2026
2013 2026

키워드

언어

전체 29건 중 1번부터 10번까지의 결과를 표시합니다.

2026
Article

Azelaic acid potentiates TRPV3 activity as a mechanism for skin irritation

  • 2026-06
  • Journal of Investigative Dermatology
  • ELSEVIER SCIENCE INC
Article

OPRM1/MRGPRX1 heterodimers drive opioid-induced itch through a peripheral mechanism

  • 2026-03
  • Journal of Biomedical Science
  • BMC
Article

Vitexin alleviates atopic dermatitis-associated itch via TRPV4 inhibition in sensory neurons and MRGPRX2/MrgprB2 blockade in mast cells

  • Kim, Yejoon ; 
  • Choi, Junhyeok ; 
  • Kim, Minjun ; 
  • Rawal, Diwas ; 
  • Lee, Wook-Joo ; 
  • ... Shim, Won-Sik
  • 2026-01
  • International Immunopharmacology
  • ELSEVIER
Article

Synthetic Strategy and Evaluation of the Benzyloxy Benzylamide Derivatives as Thymic Stromal Lymphopoietin Modulators for the Treatment of Atopic Dermatitis

  • Seo, Kyoung Hee ; 
  • Jang, Bo Ko ; 
  • Yeon, Seul Ki ; 
  • Kim, Hyeon Ji ; 
  • Lee, Ye Rim ; 
  • ... Shim, Won-Sik ; 
  • 외 10명
  • 2026-01
  • Journal of Medicinal Chemistry
  • AMER CHEMICAL SOC
2025
Article

Blockade of PAR2 Signaling by Punicalagin as a Therapeutic Strategy for Atopic Dermatitis

  • Jeon, Hyejin ; 
  • Seo, Yohan ; 
  • Lee, Wook-Joo ; 
  • Heo, Yunkyung ; 
  • Shim, Won-Sik ; 
  • 외 1명
  • 2025-09
  • International Journal of Molecular Sciences
  • MDPI
Article

Identification of KMH-45, a novel MRGPRX2 inhibitor with enhanced anti-pruritic properties

  • 2025-09
  • Biomedicine & Pharmacotherapy
  • Elsevier Masson s.r.l.
Article

Sphingosylphosphorylcholine induces itch via activation of TRPM3 and TRPA1 in mice

  • 2025-07
  • Biochemical Pharmacology
  • PERGAMON-ELSEVIER SCIENCE LTD
2024
Article

Anoctamin 1, a multi-modal player in pain and itch

  • 2024-11
  • Cell Calcium
  • ELSEVIER SCI LTD
Article

Antipruritic effect of ursolic acid through MRGPRX2/MrgprB2-dependent inhibition of mast cell degranulation and reduced TSLP production

  • Cha, Jieun ; 
  • Ryu, Juhee ; 
  • Rawal, Diwas ; 
  • Lee, Wook-Joo ; 
  • Shim, Won-Sik
  • 2024-10
  • European Journal of Pharmacology
  • ELSEVIER
Article

A phytosphingosine derivative mYG-II-6 inhibits histamine-mediated TRPV1 activation and MRGPRX2-dependent mast cell degranulation

  • Adhikari, Nisha ; 
  • Lee, Wook-Joo ; 
  • Park, Soojun ; 
  • Kim, Sanghee ; 
  • Shim, Won-Sik
  • 2024-05
  • International Immunopharmacology
  • Elsevier
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